Perillyl Extract

Introduction
To prevent toxic build-up, your body depends on healthy cells, the basic building blocks of all body tissue. These microscopic structures are the home of your body’s genetic code, and the bioprogramming center for all body processes. Every cell contains vital genetic information (DNA), which controls every phase of cellular life — including cell division (replication) and normal cell death. This biochemical code directs daily cellular activity and gives your cells their identity, telling them how to specialize in performing specific body functions as heart, lung or nerve cells (et.al.). These cells are then able to perform the functions necessary to keep your body healthy and happy throughout your life.

Unfortunately, everyone’s cells are vulnerable to miscommunication or other mistakes. For some people, genetic or environmental factors make these mistakes occur more often. These people may need extra nutritional support to encourage the body’s natural immune system to purify their cells. Perillyl Extract was designed with these people in mind. It supports the body through cell purification and encourages healthy cell function.

Benefits
Perillyl Extract helps to support cell purification and encourages cells to act in a healthy manner.

Monoterpenes, found in the essential oils of many fruits and plants, are being researched for their chemopreventive and chemotherapeutic properties. Perillyl Alcohol (POH) is one such monoterpene. Here are some results of this research (see References below):

• Monoterpenes are praised for having considerable antitumor activity, oral bioavailability, low toxicity.
• Novel mechanisms of action different from those of conventional cancer chemotherapeutic drugs.
• POH and other similar monoterpenes are particularly interesting as chemotherapeutic agents because the antitumor effects of these compounds are attained with little or no host toxicity.
• POH has been found to be even more effective than d-limonene, perillic acid, or dihydroperillic acid in causing tumor regression.
• POH works in many different ways to fight cancer and increase overall cellular health. The chemopreventive effects of POH in the body are thought to be due in part to the ability of POH to induce Phase I and Phase II liver detoxification systems. By inducing Phase II carcinogen-metabolizing liver enzymes, POH may decrease the possibility that carcinogens will cause cellular damage.
• Another mechanism by which POH is thought to fight against cancer is by inducing apoptosis. Apoptosis is the cellular self-destruction mechanism that is triggered when a cell's DNA is badly damaged. Cancer cells have the ability to bypass self-destruction and to continue proliferating at an uncontrollable rate. POH is believed to have the capability of inducing apoptosis in cancer cells without affecting normal cells.
• The chemotherapeutic properties of POH have been shown to work against neuroblastoma and cancer of the prostate, colon, pancreas, breast and liver.
• POH has been shown to not only help the body fight against existing cancerous growths, but also to help prevent the formation of cancer. There have been documented studies of POH playing a chemopreventive role in colon, skin, breast, and lung cancer.

Ingredients
Perillyl Alcohol from a lavender extract. Perillyl Extract is derived from lavender oil and limonene, which is found in lemons and oranges. This extract induces liver enzymes that enhance proper cellular function.

Usage
POH is better tolerated when taken with food. For individuals concerned with enhancing cellular health, who would like extra dietary support because they have a high risk of developing cancer, take 1 pill 4 to 5 times daily.

For individuals who would like specific nutritional support during cancer therapy, dosage is based on height and weight. If this is you, Contact me after purchasing this product and I'll email you the chart. Take the suggested dosage 4 times a day. If you experience uncomfortable side effects, take the suggested dosage for 4 days, rest for 3 days, and repeat.

Not suggested for use by children.

Contraindications and Cautions
Persons with cancer or anyone taking prescription drugs should consult with a physician before taking this or any other supplement.

Side effects may include nausea, vomiting, heartburn, loss of appetite, weight loss, fatigue, or unpleasant taste.

Pregnant or nursing women are advised to consult with a health care practitioner before taking this or any other nutritional supplement.

Purchase Information
Go to my Neways store and click on Products to access the online catalog.

Category: Nutritionals, Item #1021 Perillyl Extract, Size 150ct., Whsl $100, Retail $145.

Jones, Cindy LA. "Monoterpenes: Essence of Cancer Cure" Nutrition Science News, April 1999.

Crowell PL, Ayoubi AS, Burke YD. "Antitumorigenic effects of limonee and perillyl alcohol against pancreatic and breast cancer. In: American Institute for Cancer Research, Dietary Phytochemicals in Cancer Prevention and Treatment. New York: Plenum Press, 1996.

Crowell PL. and Gould MN. "Chemoprevention and therapy of cancer by d-limonene." CRC Critical Review Oncogenesis 1994; 5: 1-22.

Evans E, et al. "Toxicology and pharmacology of perillyl alcohol in rats and dogs." Proc Am Assoc Cancer Res 1995; 36: 366.

Haag JC and Gould MN. "Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene." Cancer Chemother Parmacol 1994; 34: 477-483

Gould MN, "Cancer chemoprevention and therapy by monoterpenes." Environ Health Prespect 1997; 105:S977-9

Crowell PL. "Prevention and therapy of cancer by dietary monoterpenes." J Nutr 1999; 129(3); 775S-778S

Ripple GH, Gould MN, Stewart JA, et al. "Phase I clinical trial of perillyl alcohol administered daily." Clin Cancer Res 1998; 4: 1159-1164

Mills JJ, Chari RS, Boyer IJ, et al. "Induction of apoptosis in liver tumors by monoterpene perillyl alcohol." Cancer Res 1995; 55:979, 983.

Schulz S, et al. "Perillic Acid inhibits Ras/MAP kinase-driven IL-2 production in human T lymphocytes." Biochem Biophys Res Commun 1997; 241: 720-725.

Elson CE. "Suppression of mevalonate pathway activities by dietary isoprenoids: protective roles in cancer and cardiovascular disease." J Nutr 1995; 125: 1666S-72S.

Broitman SA, et al. "Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic 'metastases' in vivo. Adv Exp Med Biol 1996; 402:111-130.